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Oxycodone side effect
Data source:
http://en.wikipedia.org/wiki/Oxycodone
Oxycodone
is an
opioid
analgesic
medication
synthesized from
thebaine.
It was developed in 1916 in
Germany,
as one of several new semi-synthetic opioids with several
benefits over the older traditional opiates and opioids;
morphine,
diacetylmorphine
and
codeine.
It was introduced to the pharmaceutical market as
Eukodal or
Eucodal
and Dinarkon.
Its chemical name is derived from codeine - the chemical
structures are very similar, differing only in that the hydroxyl
group of codeine has been oxidized to a carbonyl group (as in
ketones),
hence the "-one" suffix, the 7,8-dihydro-feature (codeine has a
double-bond between those two carbons), and the hydroxyl group
at carbon-14 (codeine has just a hydrogen in its place), hence
oxycodone.
Side effect
The most commonly reported effects include
constipation,
fatigue,
dizziness,
nausea,
lightheadedness,
headache,
dry mouth,
pruritus,
and
diaphoresis.
It has also claimed to cause dimness in vision due to
Miosis. Some patients have also
experienced loss of appetite, nervousness,
euphoria,
anxiety,
abdominal pain,
diarrhea,
dyspnea,
and
hiccups,[6]
although these symptoms appear in less than 5% of patients
taking oxycodone. Rarely, the drug can cause
impotence,
enlarged
prostate gland,
and decreased
testosterone
secretion.[5]
In high doses, overdoses, or in patients not tolerant to opiates, oxycodone
can cause shallow breathing,
bradycardia,
cold, clammy skin,
apnea,
hypotension,
pupil constriction,
circulatory collapse,
respiratory arrest,
and death.[6]
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