Data source: http://chealth.canoe.ca/drug_info_details.asp?brand_name_id=1618&rot=4

(conjugated estrogens vaginal cream)

Conjugated estrogens vaginal cream belongs to the class of medications known as estrogen replacement therapy. Conjugated estrogens vaginal cream is used to manage vaginal and urinary menopausal symptoms such as itching, burning, dryness in or around the vagina, difficulty or burning during urination, and painful sexual intercourse.

What side effects are possible with Premarin cream?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

       abdominal cramps, bloating

       abdominal or back pain

       breast tenderness

       clear vaginal discharge (this usually means that the medication is working properly)

       hair loss

       headache

       nausea or vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

       breast pain

       itching of the vagina or genitals

       stinging or redness in the genital area

       thick, white vaginal discharge without odour or with a mild odour

       unusual or unexpected uterine bleeding or spotting

Stop taking the medication and seek immediate medical attention if any of the following occur:

       first migraine

       severe leg pain or numbness affecting any part of the body

       shortness of breath

       sudden vision changes

       tightness of the chest

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.